Depression, Anxiety and the Gastrointestinal Tract Microbiota

It has long been known that psychological stress could negatively impact the composition of the gastrointestinal tract microbiota. Research conducted over the past decade has shown, however, that alterations in the composition of the microbiota can actually change emotional behaviour and brain function. This bidirectional relationship is now being referred to as the Brain-Gut-Microbiota axis.

In this 2-part lecture series, we’ll be exploring in depth the mechanisms by which our microbes may modify our mood - specifically depression and anxiety. We'll examine which intestinal microbes and their metabolites may be involved, as well as the investigation techniques needed to determine the health and composition of this ecosystem – particularly in relation to mood disorders.

Dr Hawrelak discusses treatment strategies aimed at improving the dysbiosis and gut dysfunction that underlies the microbiota-mood axis. He also highlights specific prebiotic and probiotic interventions that can modify the stress response, decrease systematic inflammation, improve cognition, and lift the spirits.

Lesson 1 - covers the links between dysbiotic events and alterations in mood, the mood-modifying mechanisms of the microbiota, and microbiota assessment techniques (65 mins).

Lesson 2 - covers the treatments required to alter the specific dysbiotic picture and gut dysfunction seen in depression and anxiety, as well as providing a comprehensive overview of prebiotic and probiotic interventions in the management of stress, depression, and anxiety (72 mins).

Lessons can be studied at your own time and at your own pace.